Wee2 (NM_201370) Mouse Recombinant Protein-蛋白质/抗原/多肽-试剂-生物在线
安诺伦(北京)生物科技有限公司
Wee2 (NM_201370) Mouse Recombinant Protein

Wee2 (NM_201370) Mouse Recombinant Protein

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产品名称: Wee2 (NM_201370) Mouse Recombinant Protein

英文名称: Wee2 (NM_201370) Mouse Recombinant Protein

产品编号: PM45711M5

产品价格: 0

产品产地: 美国

品牌商标: Leading Biology

更新时间: null

使用范围: null

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产品概述:Purified recombinant protein of Mouse WEE1 homolog 2 (S. pombe) (Wee2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

蛋白长度:A DNA sequence from Mouse cDNA ORF Clone, [GM38125V], encoding Mouse full-length Wee2.

表达系统:HEK293T

种属:Mouse

标签类型:C-MYC/DDK

分子量:62.2 kDa

通用名:Wee2

总结:Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation.[UniProtKB/Swiss-Prot Function]

形式:Liquid

浓度:>50 ug/mL as determined by microplate BCA method

纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

别名:Gm1065; Wee1B