产品概述：Purified recombinant protein of Human complement component 2 (C2), transcript variant 1, Ser469-End, with N-terminal His tag, expressed in E.coli, 50ug

蛋白长度：A DNA sequence encoding the region(Ser469-End) of C2

表达系统：E. coli

种属：Human

标签类型：N-His

分子量：32.0 kDa

通用名：C2

总结：Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq, Mar 2009]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：50mM Tris, 8M Urea, pH8.0.

别名：ARMD14; CO2