产品概述：Recombinant protein of human metadherin (MTDH), residues 70-582aa, with N-terminal His tag, expressed in sf9 cells

蛋白长度：A DNA sequence from GoldORF clone, [GH37128V], encoding the region(Met-Gly70-Thr582) of Homo sapiens MTDH

表达系统：Sf9

种属：Human

标签类型：N-His

分子量：56.3 kDa

通用名：MTDH

总结：Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.[UniProtKB/Swiss-Prot Function]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol

别名：3D3; AEG-1; AEG1; LYRIC; LYRIC/3D3