GRIN2B polyclonal antibody
产品名称： GRIN2B polyclonal antibody
英文名称： GRIN2B polyclonal antibody
产品编号： PAB7054
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of GRIN2B.
- Immunogen:
- A synthetic peptide corresponding to human GRIN2B.
- Sequence:
- C-KDAHEKDDFHHLS
- Host:
- Goat
- Theoretical MW (kDa):
- 166
- Reactivity:
- Rat
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:16000)
Western Blot (2-4 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- NR2A and NR2B receptor gene variations modify age at onset in Huntington disease.
Arning L, Kraus PH, Valentin S, Saft C, Andrich J, Epplen JT.Neurogenetics. 2005 Feb;6(1):25-8. Epub 2004 Nov 17.
- Entrez GeneID:
- 2904
- Protein Accession#:
- NP_000825.1
- Gene Name:
- GRIN2B
- Gene Alias:
- MGC142178,MGC142180,NMDAR2B,NR2B,hNR3
- Gene Description:
- glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- Omim ID:
- 138252
- Gene Ontology:
- Hyperlink
- Gene Summary:
- N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq
- Other Designations:
- N-methyl-D-aspartate receptor subunit 2B,glutamate receptor subunit epsilon-2
- Related Disease
- Alcohol Withdrawal Delirium
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Anorexia Nervosa
- Attention
- Attention Deficit Disorder with Hyperactivity
- Bipolar Disorder
- Bulimia
- Cognition
- Cognition Disorders
- Cues
- Disease Models, Animal
- Dyslexia
- Epilepsy
- Executive Function
- Genetic Predisposition to Disease
- Huntington Disease
- Huntington disease